|
|
The Cumming LabLed by Dr. Robert C. Cumming, our laboratory studies the changes in brain metabolism and antioxidant defence that occur with age. We are trying to understand how age-dependent alterations in metabolic and antioxidant enzyme activities contribute to neurodegenerative disorders, including Alzheimer’s disease and Huntington’s disease.
We currently are using a variety of biochemical, genetic, microscopic and neuroimaging techniques to examine aerobic glycolysis and antioxidant response in both cell culture and mouse models of aging and neurodegenerative diseases. Our lab is equipped with a cell culture and microscopy suite, a wet lab with standard molecular and biochemical instrumentation, and a behavioural facility to test memory in rodents. |
About me |
My primary research interests include: brain metabolism, redox protein signalling, and regulation of antioxidant response using cell culture and animal models of aging and disease. I run an active and well funded research lab and serve on a number of private and federal grant review committees. I received my PhD in Molecular and Medical Genetics in 2001 from the University of Toronto. Between 2001 - 2006, I completed a postdoctoral fellowship at the Salk Institute in La Jolla, California, USA. In 2007, I joined the Department of Biology at Western University and was promoted to associate professor in 2013. I currently teach undergraduate courses on cell biology and molecular mechanisms of aging.
|
|